1UP Nutrition All In One Pre Workout Review

1UP Nutrition All In One Pre Workout Review

My 1UP Nutrition All In One Pre Workout Review First Look:

It is Monday. Great…said nobody, ever.

Well maybe they did, but I bet they didn’t get absolutely hammered Friday and Saturday night then have to deal with the stress and anxiety that follows the booze.

I bet they also didn’t have to cycle to and from work in the pissing rain either.

So, all in all, today, being a Monday has been a bit shitty.

I feel lackadaisical at best and downright ill tempered at worst.

My house is still a construction site and I have a headache. Therefore, the best thing to do in my opinion is hit some deadlifts.

I am going to drink this pre workout which boasts many large figures, then I am going to disappear beneath my living room to the make shift home gym to pick some fucking weights up and put them down repeatedly.

If this doesn’t help me get over the boozy blues I think I am fucked forever.

I am also hoping this pre workout does a trick too. It is a massive 20g serving and tastes of sour apple, so in my mind this is going to be a winner.

Let’s hope so. I will see you on the other side, friends….

Ingredients: The Science

Niacin (B3)

Higher amounts of niacin can improve cholesterol levels and lower cardiovascular risks. However, the jury is out on these real benefits.



This is used as a sports performance and cardiovascular health supplement. L-Citrulline supplementation results in reduced fatigue and improved endurance for both aerobic and anaerobic prolonged exercise.

An increase in growth hormone has been noted with exercise, but not at rest.

L-citrulline boosts nitric oxide production in the body. Nitric oxide helps your arteries relax and work better, which improves blood flow throughout your body.

Supplementing can help lower blood pressure in people with pre-hypertension.

This is often found in the best pre workouts.

To supplement L-citrulline to enhance sports performance, take 6,000 – 8,000 mg of citrulline malate about an hour before exercise.




Supplementation of this non essential amino acid aids the production of carnosine. That’s a compound that plays a role in muscle endurance in high-intensity exercise.

That said, studies have not exactly been positive nor entirely conclusive.



Agmatine is considered to be a neurotransmitter and neuromodulator.

The majority use agmatine injections, not oral ingestion and there is still no evidence that working memory is enhanced with agmatine supplementation.



Tyrosine is taken for depression, attention deficit disorder (ADD), attention deficit-hyperactivity disorder (ADHD), the inability to stay awake (narcolepsy), and improving alertness following sleep deprivation.

It is also used for stress, Parkinson’s disease, Alzheimer’s disease, chronic fatigue syndrome(CFS).

Acetyl Tyrosine is a more soluble form of tyrosine.



Technically Hordenine can be used as a stimulant and fat burner due to its associated with tyramine and noradrenaline, but not enough evidence exists currently to support its usage as nutritional supplementation.



Data shows an increase in energy expenditure and kilocalorie expenditure.

It also results in a moderate increase in heart rate and systolic blood pressure similar to caffeine.



This can assist with endurance, tested athletes saw an edge from caffeine in scientific studies.

In some trials, the stimulant boosted athletes’ speed. In others, it helped them last longer before they spent all their energy.

Caffeine also raises the metabolism which means you burn more calories. Some studies show that it can curb soreness after exercise, too.

This means you could get back to your training sooner and training means more calories burnt. This is present in all 3 of our Top Fat Burners and in the best pre workout, 4GAUGE.

Caffeine Anhydrous is the purest form so always look for that.


Dicaffeine Malate

Caffeine and Malic Acid bonded. Malic acid is found in apples and the two combined help prevent the crash once the caffeine has worn off.

This is found in Mr. Hyde Cutz but very little in terms of scientific studies to be found.


L-Norvaline showed significant improvement in serum nitrates, urea, LDH, testosterone and testicular protein level in diabetic rats.

There seems to be lots of information on the web about L-norvaline being a wonder drug, however, very little can be found from reliable, scientific sources i.e websites that are not trying to sell it to us.



Beneficial for stress reduction, decreasing generalized anxiety, and reducing the severity of insomnia.

If caffeine is present too, IQ scores have known to increase – so grap a cup of coffee, quick.


Dimethylaminoethanol DMAE

This compound can help with cognitive impairment, however, results from studies are a bit patchy.

This is not classified for use as a food additive in the USA.

Has been marketed as DEANOL.



Studies show that it appears to be a safe and effective treatment for hypertension when used in appropriate low doses.

However, some adverse side effects such as lethargy, sedation, psychiatric depression, hypotension, nausea, vomiting, abdominal cramping, gastric ulceration, nightmares, bradycardia, angina-like symptoms, bronchospasm, skin rash, itching, galactorrhea, breast enlargement, sexual dysfunction, and withdrawal psychosis are not uncommon.


N-methyltyramine (NMT)

This compound is largely unstudied and therefore the limited knowledge is really based on tests from animals and rodents.

Studies do show that it inhibits fat breakdown, but being a stimulant it may just suppress appetite. Not really conclusive though.

Stohs SJ, Hartman MJ. A Review of the Receptor Binding and Pharmacological Effects of N-methyltyramine. Phytother Res. 2015 Jan;29(1):14-6.


The sachet was green apple flavor which was just like Apple Sourz liquor. I think it tastes good, too good if you are a student at University and love a drink.

The sachet was 20g and compares well to most of the best pre workout supplements we have tried.

20g is a large amount…you have been warned.



Citrulline can improve blood flow, increase nitric oxide production, lower high blood pressure, improve performance and even increase growth hormone. We need at least 8000mg for these benefits though and this delivers!

Betaine can offer power increases but only when supplemented in very large doses, much larger than this combined dose.

Tyrosine is great to improve alertness and combat tiredness or feelings of fatigue particularly after periods of no sleep.

Caffeine is a well known stimulant able to increase performance and keep you more alert while fighting fatigue.

Higenamine offers similar effects to that of Caffeine.

Theanine, when combined with Caffeine can increase IQ scores as well as reduce anxiety and stress…much needed if you have been getting drunk all weekend.

Rauwolfia if dosed in the appropriate amount can help reduce high blood pressure (hypertension).

N-methyltyramine (NMT) is a stimulant, but there’s limited research in humans of the compound.

READ: Read about our favorite pre workout that turned me in to a beast on the rugby pitch

How did it feel?

I got a slight buzz from the pre workout supplement, but nothing really to write home about.

The problem was for me anyway, any benefit I may have received was completely overshadowed by my stomach not feeling settled once I started drinking it.

I had eaten approximately 2 hours previously and my stomach felt fine to hit the deadlifts.

However, once I started drinking this I felt bloated and not particularly in a great way.

It really ruined the experience for me unfortunately.


Agmatine seems to offer no benefit when taken orally.

Beta-Alanine isn’t proven to offer any concrete benefit other than make a tingly sensation, even then I couldn’t really feel it with this particular pre workout from ANS.

Hordenine has no evidence to support any claims that they can increase athletic performance.

B3 is supposed to help reduce cholesterol and cardio vascular risks but isn’t really proven to do so.

DiCaffeine Malate has no real body of evidence at all to substantiate any claims.

Norvaline is the same, lots of chat but little hard evidence to prove it works.

DMAE is also lacking any real concrete evidence to fulfill the chat on the internet about it.

Rauwolfia can be harmful if not dosed correctly, therefore take with caution.

N-methyltyramine (NMT) is sometimes found in fat burners, however, no to little human testing or trials means that the only few studies have been on animals. It is a stimulant but more evidence or tests in humans is really required.

However, the worse thing was the stomach upset and bloat that I faced. This may not be experienced by everyone but for me, it eclipsed any possible benefits.

This is not a pre workout I would use again, especially not for weight training or playing rugby.

1UP Nutrition All In One Pre Workout Review Conclusion:

In many respects this is a good pre workout.

There’s a good number of effective and properly dosed ingredients that could help take your training to the next level.

However, it also includes a large number of ingredients that are just not proven to be effective, and this is unacceptable really considering there are effective and beneficial pre workout supplements on the market whereby all of their ingredients are proven to help and they also do not cause stomach bloat or upset.

This is the major flow for me.

a) stomach bloat is unpleasant and hinders performance (for me anyway)

b) why aren’t all of the ingredients included prove to be effective?

Just dump the dud ones and replace them with beneficial ingredients.

Take a look at what I have felt to be the best performing pre workout supplements available, here.

Ben BA(Hons), PGCert

Ben established this site to be a free resource in 2015. Since then it has gained over half a million visits. He has always been interested in sport and he started playing rugby at the age of 6 represented his town, county and school. Ben also enjoys cycling, has started skiing and is in the Army Reserve representing his Regiment as part of the 150 Regimental Shooting Team. He holds a bachelor's and postgraduate degree in sport exercise & nutrition.

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